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Anti-Human AGTR2/AT2 Recombinant Antibody (4A03), PerCP (HW681147)

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Overview
Catalog No.HW681147
Description
Anti-Human AGTR2/AT2 Recombinant Antibody (4A03), PerCP (HW681147) is a mouse monoclonal antibody detecting AGTR2/AT2 in FCM. Suitable for Human.
Highlights
  • ●PerCP Conjugated — Ready for direct detection without secondary antibody.
Species reactivityHuman
ApplicationsFCM
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG1, kappa
Clone ID4A03
ConjugationPerCP
Target AGTR2, Angiotensin II type-2 receptor, Type-2 angiotensin II receptor, AT2
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Associated products Mouse IgG1 kappa Recombinant Isotype Control Antibody (MOPC-21), PerCP
Accession P50052
Form Liquid
Storage buffer 0.01M PBS pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Type-2 angiotensin II receptor (AGTR2/AT2) is a ~41 kDa protein. Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

1. Zhang, H. et al. (2017) Nature 544, 327-332. PMID: 28379944
2. Asada, H. et al. (2018) Nature structural & molecular biology 25, 570-576. PMID: 29967536
3. Asada, H. et al. (2020) Structure (London, England : 1993) 28, 418-425.e4. PMID: 31899086
4. Tsuzuki, S. et al. (1994) Biochemical and biophysical research communications 200, 1449-54. PMID: 8185599
5. Nouet, S. et al. (2004) The Journal of biological chemistry 279, 28989-97. PMID: 15123706
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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