

| Catalog No. | HC599013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG2a, kappa | ||||
| Clone ID | SAA1667 | ||||
| Clonality | Monoclonal | ||||
| Target | Protein JTV-1, Multisynthase complex auxiliary component p38, AIMP2, JTV1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q13155 | ||||
| RRID | Anti-Human AIMP2 Antibody (SAA1667) (abinScience Cat# HC599013, RRID:AB_3727428) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) is a ~35 kDa protein. Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. 1. Kaminska, M. et al. (2009) The Journal of biological chemistry 284, 6053-60. PMID: 19131329 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human AIMP2 Antibody (SAA1667)
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