Anti-Human AIMP2 Polyclonal Antibody (HC599014)

Name: Anti-Human AIMP2 Polyclonal Antibody
Brand: abinScience
SKU: HC599014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HC599014

Description

Anti-Human AIMP2 Polyclonal Antibody (HC599014) is a rabbit polyclonal antibody detecting AIMP2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Cricetulus griseus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human AIMP2 (Lys120-Lys320).

Target

Protein JTV-1, Multisynthase complex auxiliary component p38, AIMP2, JTV1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Purification

Purified by antigen affinity column.

Accession

Q13155

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) is a ~35 kDa protein. Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

1. Kaminska, M. et al. (2009) The Journal of biological chemistry 284, 6053-60. PMID: 19131329

Note

For research use only.

Images

References

Datasheet

Anti-Human AIMP2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human AIMP2 Polyclonal Antibody (HC599014)

Overview

Images

References

Datasheet

SDS

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