Anti-Human AQP4/Aquaporin-4 Recombinant Antibody (SAA1755) (HX181013)

Name: Anti-Human AQP4/Aquaporin-4 Recombinant Antibody (SAA1755)
Brand: abinScience
SKU: HX181013
Price: 110 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HX181013

Species reactivity

Human

Applications

ELISA, FCM, IF

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1755

Clonality

Monoclonal

Target

WCH4, Aquaporin-4, Mercurial-insensitive water channel, AQP-4, MIWC, AQP4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P55087

RRID

Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755) (abinScience Cat# HX181013, RRID:AB_3727516)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Aquaporin-4 (AQP4) is a ~34 kDa protein. Forms a water-specific channel. Plays an important role in brain water homeostasis. It is involved in glymphatic solute transport and is required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP.

1. Ho, JD. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 7437-42. PMID: 19383790

2. Yang, B. et al. (1995) The Journal of biological chemistry 270, 22907-13. PMID: 7559426

3. Misaka, T. et al. (1996) FEBS letters 381, 208-12. PMID: 8601457

4. Passchier, EMJ. et al. (2023) Brain : a journal of neurology 146, 3444-3454. PMID: 37143309

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755).

References

Datasheet

Anti-Human AQP4/Aquaporin-4 Recombinant Antibody (SAA1755).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human AQP4/Aquaporin-4 Recombinant Antibody (SAA1755) (HX181013)

Overview

Images

References

Datasheet

SDS

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