Anti-Human CADM1 Recombinant Antibody (SAA1897) (HA183013)

Name: Anti-Human CADM1 Recombinant Antibody (SAA1897)
Brand: abinScience
SKU: HA183013
Price: 110 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HA183013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1897

Clonality

Monoclonal

Target

SgIgSF, Immunoglobulin superfamily member 4, SynCAM, IGSF4A, SYNCAM, TSLC1, Synaptic cell adhesion molecule, IgSF4, Tumor suppressor in lung cancer 1, TSLC-1, CADM1, Spermatogenic immunoglobulin superfamily, Nectin-like protein 2, Cell adhesion molecule 1, NECL2, IGSF4, NECL-2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9BY67

RRID

Anti-Human CADM1 Antibody (SAA1897) (abinScience Cat# HA183013, RRID:AB_3727661)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Cell adhesion molecule 1 (CADM1) is a ~48 kDa protein. Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo.

1. Masuda, M. et al. (2002) The Journal of biological chemistry 277, 31014-9. PMID: 12050160

2. Moiseeva, EP. et al. (2012) Cellular and molecular life sciences : CMLS 69, 2751-64. PMID: 22438059

3. Boles, KS. et al. (2005) Blood 106, 779-86. PMID: 15811952

4. Furuno, T. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 174, 6934-42. PMID: 15905536

5. Kuramochi, M. et al. (2001) Nature genetics 27, 427-30. PMID: 11279526

6. Yageta, M. et al. (2002) Cancer research 62, 5129-33. PMID: 12234973

7. Ito, A. et al. (2003) Laboratory investigation; a journal of technical methods and pathology 83, 1175-83. PMID: 12920246

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CADM1 Antibody (SAA1897)

References

Datasheet

Anti-Human CADM1 Recombinant Antibody (SAA1897).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human CADM1 Recombinant Antibody (SAA1897) (HA183013)

Overview

Images

References

Datasheet

SDS

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