Anti-Human Calprotectin/S100A8 & S100A9 Monoclonal Antibody (1A316) (HY242015)

Name: Anti-Human Calprotectin/S100A8 & S100A9 Monoclonal Antibody (1A316)
Brand: abinScience
SKU: HY242015
Price: 194 USD
Availability: InStock

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Overview

Catalog No.	HY242015
Description	Anti-Human Calprotectin (S100A8/S100A9) Monoclonal Antibody (1A316) [1A316] (HY242015) is a mouse monoclonal antibody detecting S100A8 in GICA, IFA. Suitable for Human.
Species reactivity	Human
Applications	GICA, IFA
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG
Clone ID	1A316
Immunogen	Human Calprotectin (S100A8/S100A9) Protein.
Target	Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CFAG, Leukocyte L1 complex light chain, Migration inhibitory factor-related protein 8, MRP-8, p8, S100 calcium-binding protein A8, Urinary stone protein band A, S100A8, CAGA, CFAG, MRP8, Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9, S100A9, CAGB, CFAG, MRP14
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Protein S100-A8 (Calprotectin (S100A8/9)) is a ~10 kDa protein. S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69. 1. Lin, CR. et al. (2015) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 29, 5006-17. PMID: 26296369
Note	For research use only.

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Datasheet

Anti-Human Calprotectin/S100A8 & S100A9 Monoclonal Antibody (1A316).pdf

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Anti-Human Calprotectin/S100A8 & S100A9 Monoclonal Antibody (1A316) (HY242015)

Overview

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