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Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460) (HB190105)

Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460)
Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460)
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Overview
Catalog No.HB190105
Description
Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460) [1A460] (HB190105) is a mouse monoclonal antibody detecting Calreticulin in FCM, WB. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivityHuman
ApplicationsFCM, WB
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG2a
Clone ID1A460
Target Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, grp60, CALR, CRTC
Endotoxin level Please contact with the lab for this information.
Purification Protein A/G purified from cell culture supernatant.
Accession P27797
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Calreticulin is a ~48 kDa protein. Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.

1. Nauseef, WM. et al. (1995) The Journal of biological chemistry 270, 4741-7. PMID: 7876246
2. Holaska, JM. et al. (2001) The Journal of cell biology 152, 127-40. PMID: 11149926
Note For research use only.
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  • Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460)

    SDS-PAGE

    SDS-PAGE for Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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