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Anti-Human CBX1 Recombinant Antibody (SAA2129) (HX177023)

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Anti-Human CBX1 Recombinant Antibody (SAA2129)
Anti-Human CBX1 Recombinant Antibody (SAA2129)
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Overview
Catalog No.HX177023
Species reactivityHuman
ApplicationsELISA, IF, IP
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG2a
Clone IDSAA2129
Target CBX1, CBX, Chromobox protein homolog 1, HP1Hsbeta, Heterochromatin protein 1 homolog beta, HP1 beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P83916
RRID Anti-Human CBX1 Antibody (SAA2129) (abinScience Cat# HX177023, RRID:AB_3729482)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Chromobox protein homolog 1 (CBX1) is a ~21 kDa protein. Component of heterochromatin, which recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Also recognizes and binds histone H1.4 methylated at 'Lys-26' (H1.4K26me). Excluded from chromatin when histone H1.4 is Simultaneously methylated at Lys-26 (H1.4K26me) and phosphorylated at Ser-27 (H1.4S27Ph). Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.

1. Daujat, S. et al. (2005) The Journal of biological chemistry 280, 38090-5. PMID: 16127177
Note For research use only.
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    SDS-PAGE

    SDS-PAGE for Anti-Human CBX1 Antibody (SAA2129)

References
Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human CBX1 Recombinant Antibody (SAA2129)

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