Anti-Human CCR4 Polyclonal Antibody (HW634014)

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Overview
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Datasheet
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Overview

Catalog No.

HW634014

Description

Anti-Human CCR4 Polyclonal Antibody (HW634014) is a rabbit polyclonal antibody detecting CCR4. Suitable for Human.

Species reactivity

Homo sapiens (Human)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CCR4 (Asn2-Glu39&Ser176-Ile206&Glu309-Leu360).

Target

C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CCR4, CD194, CMKBR4, K5-5

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P51679

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

C-C chemokine receptor type 4 (CCR4) is a ~41 kDa protein. High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Note

For research use only

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References

Datasheet