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Anti-Human CCR4 Reference Antibody (KM3060, RUO) (HW634026)

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Anti-Human CCR4 Reference Antibody (KM3060, RUO)

Anti-Human CCR4 Reference Antibody (KM3060, RUO)

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100ug
1mg

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Datasheet
SDS

Overview

Catalog No.	HW634026
Description	Anti-Human CD194/CCR4 Antibody (KM3060) (HW634026) is a research-grade recombinant antibody targeting CD194. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Chimeric
Isotype	IgG
Clone ID	KM3060
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	K5-5, CCR4, C-C CKR-4, CD194, CC-CKR-4, CCR-4, C-C chemokine receptor type 4, CMKBR4
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P51679
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	C-C chemokine receptor type 4 (CD194/CCR4) is a ~41 kDa protein. High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD194/CCR4 Antibody (KM3060)

References

Datasheet

Anti-Human CCR4 Reference Antibody (KM3060, RUO).pdf

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Formula

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Anti-Human CCR4 Reference Antibody (KM3060, RUO)