

| Catalog No. | HW634137 |
|---|---|
| Description |
Anti-Human CD194/CCR4 Antibody (SAA0069), APC [SAA0069] (HW634137) is a mouse monoclonal antibody detecting CD194 in FCM. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG2a, kappa |
| Clone ID | SAA0069 |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | K5-5, CCR4, C-C CKR-4, CD194, CC-CKR-4, CCR-4, C-C chemokine receptor type 4, CMKBR4 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P51679 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | C-C chemokine receptor type 4 (CD194/CCR4) is a ~41 kDa protein. High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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