Anti-Human CD10/MME Recombinant Antibody (A1) (HY401013)

Name: Anti-Human CD10/MME Recombinant Antibody (A1)
Brand: abinScience
SKU: HY401013
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY401013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG1, kappa

Clone ID

Clonality

Monoclonal

Target

Neprilysin, EC:3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P08473

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Neprilysin (CD10/MME) is a ~85 kDa protein. Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)).

1. Rice, GI. et al. (2004) The Biochemical journal 383, 45-51. PMID: 15283675

2. Skidgel, RA. et al. (1984) Peptides 5, 769-76. PMID: 6208535

3. Gafford, JT. et al. (1983) Biochemistry 22, 3265-71. PMID: 6349683

4. Le Moual, H. et al. (1994) European journal of biochemistry 221, 475-80. PMID: 8168535

5. Wisner, A. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 17979-84. PMID: 17101991

6. Brandt, I. et al. (2006) Clinical chemistry 52, 82-7. PMID: 16254193

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD10/MME Antibody (A1)

References

Datasheet

Anti-Human CD10/MME Recombinant Antibody (A1).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CD10/MME Recombinant Antibody (A1) (HY401013)

Overview

Images

References

Datasheet

SDS

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