Anti-Human CD120a/TNFRSF1A/TNFR1 Recombinant Nanobody (Clone: 70) (HB895023)

Name: Anti-Human CD120a/TNFRSF1A/TNFR1 Recombinant Nanobody (Clone: 70)
Brand: abinScience
SKU: HB895023
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB895023

Description

Anti-Human CD120a/TNFRSF1A/TNFR1 Nanobody (Clone: 70) [Clone: 70] (HB895023) is a alpaca monoclonal antibody detecting TNFRSF1A in ELISA, FuncS. Suitable for Human.

Species reactivity

Human

Applications

ELISA, FuncS

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clone ID

Clone: 70

Clonality

Monoclonal

Target

TNFR-I, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, TBPI, p60, CD120a, TNFRSF1A, Tumor necrosis factor receptor type I, p55, TNF-RI, TNFAR, TNFR1, TNF-R1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P19438

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Tumor necrosis factor receptor superfamily member 1A (CD120a/TNFR1) is a ~50 kDa protein. Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD120a/TNFRSF1A/TNFR1 Nanobody (Clone: 70)
Bioactivity

Detects recombinant CD120a (Catalog No: HB895011) in indirect ELISA.