Anti-Human PDGF R alpha Recombinant Antibody (SAA0057) (HB927207)

Name: Anti-Human PDGF R alpha Recombinant Antibody (SAA0057)
Brand: abinScience
SKU: HB927207
Price: 191 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.	HB927207
Species reactivity	Human
Applications	ELISA, FCM, IHC, WB
Host species	Human
Isotype	IgG2, kappa
Clone ID	SAA0057
Clonality	Monoclonal
Target	PDGFR2, Platelet-derived growth factor receptor alpha, RHEPDGFRA, Alpha platelet-derived growth factor receptor, PDGFR-2, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGF-R-alpha, Alpha-type platelet-derived growth factor receptor, CD140a antigen, CD140 antigen-like family member A, PDGFRA, PDGFR-alpha, CD140a
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P16234
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Platelet-derived growth factor receptor alpha (CD140a/PDGFRA) is a ~122 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi.
Note	For research use only.

Images

Bioactivity

SEC-HPLC detection for Anti-Human CD140a/PDGFRA Antibody (ABS0556).
Flow Cytometry

Flow-cytometry using anti-human CD140a antibody. Human MG-63 cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human CD140a antibody monoclonal antibody (Catalog # HB927207 , Red Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-CD140a/PDGFRA monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD140a/PDGFRA (Catalog No: HB927011)