Anti-Human CD147/BSG Recombinant Antibody (SAA2740) (HW664033)

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50ug
100ug
1mg

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SDS

Overview

Catalog No.

HW664033

Description

Anti-Human CD147/BSG Antibody (SAA2740) [SAA2740] (HW664033) is a mouse monoclonal antibody detecting CD147 in ELISA, FCM, WB. Suitable for Human.

Highlights

●Multi-Application — Validated across multiple applications.
●Flow Cytometry — Validated for flow cytometry applications.

Species reactivity

Human

Applications

ELISA, FCM, WB

Host species

Mouse

Isotype

IgG1, kappa

Clone ID

SAA2740

Clonality

Monoclonal

Target

5F7, BSG, Basigin, CD147, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, HAb18G, Hepatoma-associated antigen, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P35613

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes.

1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687

2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857

Note

For research use only

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Datasheet