Anti-Human CD150/SLAMF1 Recombinant Antibody (SAA1581) (HC275013)

Name: Anti-Human CD150/SLAMF1 Recombinant Antibody (SAA1581)
Brand: abinScience
SKU: HC275013
Price: 196 USD
Availability: InStock

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1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC275013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1581

Clonality

Monoclonal

Target

SLAM family member 1, IPO-3, CDw150, SLAMF1, SLAM, CD150, Signaling lymphocytic activation molecule

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13291

RRID

Anti-Human CD150/SLAMF1 Antibody (SAA1581) (abinScience Cat# HC275013, RRID:AB_3727342)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Signaling lymphocytic activation molecule (CD150/SLAMF1) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

1. Howie, D. et al. (2002) Blood 99, 957-65. PMID: 11806999

2. Li, C. et al. (2003) The Journal of biological chemistry 278, 3852-9. PMID: 12458214

3. Réthi, B. et al. (2006) Blood 107, 2821-9. PMID: 16317102

4. Yurchenko, MY. et al. (2010) Immunology and cell biology 88, 565-74. PMID: 20231852

5. Berger, SB. et al. (2010) Nature immunology 11, 920-7. PMID: 20818396

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD150/SLAMF1 Antibody (SAA1581)

References

Datasheet

Anti-Human CD150/SLAMF1 Recombinant Antibody (SAA1581).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CD150/SLAMF1 Recombinant Antibody (SAA1581) (HC275013)

Overview

Images

References

Datasheet

SDS

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