

| Catalog No. | HT302024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human CD172b/SIRPB1 (Glu39-Glu347). | ||||||||
| Target | SIRP-beta-1, Signal-regulatory protein beta-1, CD172 antigen-like family member B, SIRPB1, CD172b | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O00241 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Signal-regulatory protein beta-1 (CD172b/SIRPB1) is a ~43 kDa protein. Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Also participates in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP. 1. Dietrich, J. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 9-12. PMID: 10604985 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-SIRPB1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: U937 cell lysate
Lane 2: PC-3 cell lysate
Lane 3: A549 cell lysate
Lane 4: HUVEC cell lysate
Lane 5: Hela cell lysate
Lane 6: Jurkat cell lysate
Lane 7: Mouse brain lysate
Lane 8: Mouse heart lysate
Lane 9: Mouse cerebellum lysate
Lane 10: Rat brain lysate
Lane11: Rat heart lysate
Lane12: Rat cerebellum lysate




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