

| Catalog No. | HT302014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human SIRPB1 (Ser127-Gly356). | ||||||||
| Target | SIRP-beta-1, Signal-regulatory protein beta-1, CD172 antigen-like family member B, SIRPB1, CD172b | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O00241 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Signal-regulatory protein beta-1 (CD172b/SIRPB1) is a ~43 kDa protein. Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Also participates in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP. 1. Dietrich, J. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 9-12. PMID: 10604985 | ||||||||
| Note | For research use only. |




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