

| Catalog No. | HC566014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human CD215/IL15RA Polyclonal Antibody (HC566014) is a rabbit polyclonal antibody detecting IL15RA in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human CD215/IL15RA (Cys33-Pro104). | ||||||||
| Target | Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, CD215, Soluble interleukin-15 receptor subunit alpha, sIL-15 receptor subunit alpha, sIL-15R-alpha, sIL-15RA, IL15RA | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q13261 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Interleukin-15 receptor subunit alpha (CD215/IL15RA) is a ~28 kDa protein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner. Expression of different isoforms may alter or interfere with signal transduction. 1. Anderson, DM. et al. (1995) The Journal of biological chemistry 270, 29862-9. PMID: 8530383 2. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770 3. Dubois, S. et al. (1999) The Journal of biological chemistry 274, 26978-84. PMID: 10480910 | ||||||||
| Note | For research use only. |



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