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Anti-Human CD242/ICAM4 Recombinant Antibody (SAA1587) (HC421013)

Anti-Human CD242/ICAM4 Recombinant Antibody (SAA1587)
Anti-Human CD242/ICAM4 Recombinant Antibody (SAA1587)
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Overview
Catalog No.HC421013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1587
Clonality Monoclonal
Target LW, Landsteiner-Wiener blood group glycoprotein, Intercellular adhesion molecule 4, ICAM4, ICAM-4, LW blood group protein, CD242
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q14773
RRID Anti-Human CD242/ICAM4 Antibody (SAA1587) (abinScience Cat# HC421013, RRID:AB_3727348)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Intercellular adhesion molecule 4 (CD242/ICAM4) is a ~29 kDa protein. Functions as a receptor ligand for the monocyte/macrophage-specific ITGAX:ITGB2 integrin complex and mediates erythrophagocytosis. Receptor ligand of the platelet-specific ITGA2B:ITGB3 integrin complex involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets. In vitro, is also a receptor ligand of multiple integrin receptors complexes such ITGAL:ITGB2, ITGAM:ITGB2, ITGA5:ITGB1, ITGA5:ITGB3 and ITGA5:ITGB5 integrin complexes.

1. Ihanus, E. et al. (2007) Blood 109, 802-10. PMID: 16985175
2. Hermand, P. et al. (2003) The Journal of biological chemistry 278, 4892-8. PMID: 12477717
3. Hermand, P. et al. (2004) European journal of biochemistry 271, 3729-40. PMID: 15355350
4. Hermand, P. et al. (2000) The Journal of biological chemistry 275, 26002-10. PMID: 10846180
5. Spring, FA. et al. (2001) Blood 98, 458-66. PMID: 11435317
Note For research use only.
Images
  • Anti-Human CD242/ICAM4 Recombinant Antibody (SAA1587)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD242/ICAM4 Antibody (SAA1587)

References
Formula
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