Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (HW1), APC (HT348437)

Name: Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (HW1), APC
Brand: abinScience
SKU: HT348437
Price: 256 USD
Availability: InStock

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Overview

Catalog No.	HT348437
Species reactivity	Human
Applications	ELISA, FCM, IF
Host species	Mouse
Isotype	IgG2a
Clone ID	HW1
Conjugation	APC
Clonality	Monoclonal
Target	TRAILR2, TRAIL-R2, Death receptor 5, CD262, DR5, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9, TRAIL receptor 2, TRICK2, TNFRSF10B, KILLER, TNF-related apoptosis-inducing ligand receptor 2
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
Accession	O14763
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Tumor necrosis factor receptor superfamily member 10B (CD262/TRAIL-R2) is a ~47 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. 1. Hymowitz, SG. et al. (1999) Molecular cell 4, 563-71. PMID: 10549288
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (HW1), APC.pdf

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Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (HW1), APC (HT348437)

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