Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (HW1) (HT348407)

Name: Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (HW1)
Brand: abinScience
SKU: HT348407
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HT348407
Species reactivity	Human
Applications	ELISA, FCM, IF, SPR
Host species	Mouse
Isotype	IgG2a
Clone ID	HW1
Clonality	Monoclonal
Target	TRAILR2, TRAIL-R2, Death receptor 5, CD262, DR5, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9, TRAIL receptor 2, TRICK2, TNFRSF10B, KILLER, TNF-related apoptosis-inducing ligand receptor 2
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O14763
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Tumor necrosis factor receptor superfamily member 10B (CD262/TRAIL-R2) is a ~47 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. 1. Hymowitz, SG. et al. (1999) Molecular cell 4, 563-71. PMID: 10549288
Note	For research use only.

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SDS-PAGE for Anti-Human CD262/TNFRSF10B/TRAIL-R2/DR5 Antibody (HW1)

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Datasheet

Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (HW1).pdf

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Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (HW1) (HT348407)

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