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Anti-Human CD30/TNFRSF8 Recombinant Antibody (SGN-35), PE (HB038127)

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Overview
Catalog No.HB038127
Description
Anti-Human CD30/TNFRSF8 Antibody (SGN-35), PE [SGN-35] (HB038127) is a rabbit monoclonal antibody detecting TNFRSF8 in FCM. Suitable for Human.
Highlights
  • Rabbit Monoclonal — High specificity, affinity, and excellent lot-to-lot consistency.
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivityHuman
ApplicationsFCM
Host speciesRabbit
IsotypeIgG
Clone IDSGN-35
ConjugationPE
Clonality Monoclonal
Target CD30L receptor, Ki-1 antigen, CD30, TNFRSF8, D1S166E, Tumor necrosis factor receptor superfamily member 8, Lymphocyte activation antigen CD30
Endotoxin level Please contact with the lab for this information.
Accession P28908
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Tumor necrosis factor receptor superfamily member 8 (CD30/TNFRSF8) is a ~63 kDa protein. Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. CD30 is the therapeutic target of brentuximab vedotin (Adcetris).

1. Smith, CA. et al. (1993) Cell 73, 1349-60. PMID: 8391931
2. Aizawa, S. et al. (1997) The Journal of biological chemistry 272, 2042-5. PMID: 8999898
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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