Anti-Human DLEC/CLEC4C/BDCA-2 Recombinant Antibody (122A2) (HV560107)

Name: Anti-Human DLEC/CLEC4C/BDCA-2 Recombinant Antibody (122A2)
Brand: abinScience
SKU: HV560107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HV560107
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	122A2
Clonality	Monoclonal
Target	CLEC4C, C-type lectin superfamily member 7, CLECSF11, C-type lectin domain family 4 member C, Dendritic lectin, CD303, DLEC, HECL, Blood dendritic cell antigen 2, BDCA-2, BDCA2, CLECSF7
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q8WTT0
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	C-type lectin domain family 4 member C (CD303/CLEC4C) is a ~25 kDa protein. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. 1. Dzionek, A. et al. (2001) The Journal of experimental medicine 194, 1823-34. PMID: 11748283 2. Riboldi, E. et al. (2011) The Journal of biological chemistry 286, 35329-35333. PMID: 21880719 3. Jégouzo, SA. et al. (2015) The Journal of biological chemistry 290, 16759-71. PMID: 25995448
Note	For research use only.

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SDS-PAGE for Anti-Human CD303/CLEC4C Antibody (122A2)

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Datasheet

Anti-Human DLEC/CLEC4C/BDCA-2 Recombinant Antibody (122A2).pdf

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Anti-Human DLEC/CLEC4C/BDCA-2 Recombinant Antibody (122A2) (HV560107)

Overview

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Datasheet

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