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Anti-Human CD303/CLEC4C Antibody (122A2), PerCP (HV560147)

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Overview

Catalog No.	HV560147
Description	Anti-Human CD303/CLEC4C Antibody (122A2), PerCP [122A2] (HV560147) is a mouse monoclonal antibody detecting CLEC4C in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	122A2
Conjugation	PerCP
Clonality	Monoclonal
Target	CLEC4C, C-type lectin superfamily member 7, CLECSF11, C-type lectin domain family 4 member C, Dendritic lectin, CD303, DLEC, HECL, Blood dendritic cell antigen 2, BDCA-2, BDCA2, CLECSF7
Endotoxin level	Please contact with the lab for this information.
Accession	Q8WTT0
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	C-type lectin domain family 4 member C (CD303/CLEC4C) is a ~25 kDa protein. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. 1. Dzionek, A. et al. (2001) The Journal of experimental medicine 194, 1823-34. PMID: 11748283 2. Riboldi, E. et al. (2011) The Journal of biological chemistry 286, 35329-35333. PMID: 21880719 3. Jégouzo, SA. et al. (2015) The Journal of biological chemistry 290, 16759-71. PMID: 25995448
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human CD303/CLEC4C Antibody (122A2), PerCP.pdf

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Anti-Human CD303/CLEC4C Antibody (122A2), PerCP