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Anti-Human FCRL5 Recombinant Antibody (SAA0316) (HV698107)

Anti-Human FCRL5 Recombinant Antibody (SAA0316)
Anti-Human FCRL5 Recombinant Antibody (SAA0316)
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Overview
Catalog No.HV698107
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA0316
Clonality Monoclonal
Target FcRL5, FCRH5, FCRL5, Fc receptor homolog 5, FcRH5, CD307e, FcR-like protein 5, IRTA2, Immune receptor translocation-associated protein 2, BXMAS1, Fc receptor-like protein 5, CD307
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q96RD9
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Fc receptor-like protein 5 (CD307e/FCRL5) is a ~106 kDa protein. Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization.

1. Franco, A. et al. (2018) International immunology 30, 569-578. PMID: 30107486
Note For research use only.
Images
  • Anti-Human FCRL5 Recombinant Antibody (SAA0316)

    Bioactivity

    Detects Recombinant Human CD307e/FCRL5 Protein, C-His (Cat No.: HV698021) in indirect ELISA.

References
Formula
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