Anti-Human FCRL5 Reference Antibody (DFRF 4539A, RUO) (HV698036)

Name: Anti-Human FCRL5 Reference Antibody (DFRF 4539A, RUO)
Brand: abinScience
SKU: HV698036
Price: 370 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.	HV698036
Description	Anti-Human CD307e/FCRL5 Antibody (DFRF 4539A) (HV698036) is a research-grade recombinant antibody targeting CD307. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Clone ID	DFRF 4539A
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Fc receptor-like protein 5, FcR-like protein 5, FcRL5, BXMAS1, Fc receptor homolog 5, FcRH5, Immune receptor translocation-associated protein 2, CD307e, FCRL5, FCRH5, IRTA2, UNQ503/PRO820
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q96RD9
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	DFRF4539A, DFRF-4539A, DFRF4539A, RG7598, RG-7598, RG7598
Background	Fc receptor-like protein 5 (CD307e/FCRL5) is a ~106 kDa protein. Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization. 1. Franco, A. et al. (2018) International immunology 30, 569-578. PMID: 30107486
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD307e/FCRL5 Antibody (DFRF 4539A)
Bioactivity

Detects recombinant human CD307e/FCRL5 (Catalog No: HV698011) in indirect ELISA