Anti-Human CD32b/FCGR2B Recombinant Nanobody (SAA2572) (HB103023)

Name: Anti-Human CD32b/FCGR2B Recombinant Nanobody (SAA2572)
Brand: abinScience
SKU: HB103023
Price: 126 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB103023

Description

Anti-Human CD32b/FCGR2B Nanobody (SAA2572) [SAA2572] (HB103023) is a alpaca monoclonal antibody detecting FCGR2B in ELISA. Suitable for Human.

Species reactivity

Human

Applications

ELISA

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clone ID

SAA2572

Clonality

Monoclonal

Target

CD32, CDw32, FCG2, FCGR2B, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, IGFR2, IgG Fc receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-b

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column.

Accession

P31994

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Low affinity immunoglobulin gamma Fc region receptor II-b (CD32b/FCGR2B) is a ~34 kDa protein. Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis.

Note

For research use only

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