Anti-Human CD358/TNFRSF21 Recombinant Antibody (M53-E04), APC (HF685137)

Name: Anti-Human CD358/TNFRSF21 Recombinant Antibody (M53-E04), APC
Brand: abinScience
SKU: HF685137
Price: 290 USD
Availability: InStock

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Overview

Catalog No.	HF685137
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	M53-E04
Conjugation	APC
Clonality	Monoclonal
Target	DR6, Death receptor 6, Tumor necrosis factor receptor superfamily member 21, TNFRSF21, CD358
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession	O75509
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Tumor necrosis factor receptor superfamily member 21 (CD358/TNFRSF21) is a ~71 kDa protein. Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation. 1. Zhang, JY. et al. (2021) Cell research 31, 980-997. PMID: 34012073
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD358/TNFRSF21 Recombinant Antibody (M53-E04), APC.pdf

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Anti-Human CD358/TNFRSF21 Recombinant Antibody (M53-E04), APC (HF685137)

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