Anti-Human CD43 Recombinant Antibody (SAA0015) (HB263107)

Name: Anti-Human CD43 Recombinant Antibody (SAA0015)
Brand: abinScience
SKU: HB263107
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HB263107
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA0015
Clonality	Monoclonal
Target	GPL115, Leukocyte sialoglycoprotein, Leukosialin, Sialophorin, SPN, Galactoglycoprotein, CD43, CD43ct, CD43-ct, GALGP
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P16150
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Leukosialin (CD43/SPN) is a ~40 kDa protein. Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN). Negatively regulates Th2 cell differentiation and predisposes the differentiation of T-cells towards a Th1 lineage commitment. Promotes the expression of IFN-gamma by T-cells during T-cell receptor (TCR) activation of naive cells and induces the expression of IFN-gamma by CD4(+) T-cells and to a lesser extent by CD8(+) T-cells. Plays a role in preparing T-cells for cytokine sensing and differentiation into effector cells by inducing the expression of cytokine receptors IFNGR and IL4R, promoting IFNGR and IL4R signaling and by mediating the clustering of IFNGR with TCR. 1. Ramírez-Pliego, O. et al. (2007) BMC immunology 8, 30. PMID: 18036228 2. Galindo-Albarrán, AO. et al. (2014) Journal of cellular physiology 229, 172-80. PMID: 24328034
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-Human CD43/SPN Antibody (ABS0999).
SDS-PAGE

SDS-PAGE for Anti-Human CD43 Recombinant Antibody (SAA0015)

References

Datasheet

Anti-Human CD43 Recombinant Antibody (SAA0015).pdf

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Anti-Human CD43 Recombinant Antibody (SAA0015) (HB263107)

Overview

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Datasheet

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