Anti-Human CD49f/ITGA6 Recombinant Antibody (P2D10) (HB157107)

Name: Anti-Human CD49f/ITGA6 Recombinant Antibody (P2D10)
Brand: abinScience
SKU: HB157107
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HB157107
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	P2D10
Clonality	Monoclonal
Target	CD49 antigen-like family member F, Integrin alpha-6, ITGA6, VLA-6, CD49f, Alpha6p
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P23229
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Integrin alpha-6 (CD49f/ITGA6) is a ~126 kDa protein. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. 1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 2. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760 3. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464
Note	For research use only.

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SDS-PAGE for Anti-Human CD49f/ITGA6 Antibody (P2D10)

References

Datasheet

Anti-Human CD49f/ITGA6 Recombinant Antibody (P2D10).pdf

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Anti-Human CD49f/ITGA6 Recombinant Antibody (P2D10) (HB157107)

Overview

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Datasheet

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