

| Catalog No. | HY465137 |
|---|---|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Human |
| Isotype | IgG1 |
| Clone ID | SP7219 |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | HLA-DR antigens-associated invariant chain, HLA class II histocompatibility antigen gamma chain, CD74, CLIP, Ia antigen-associated invariant chain, DHLAG, Ii |
| Endotoxin level | Please contact with the lab for this information. |
| Associated products | Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC |
| Accession | P04233 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | HLA class II histocompatibility antigen gamma chain (CD74) is a ~33 kDa protein. Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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