Anti-Human CIAO1 IP Recombinant Antibody (SAA0198) (HF508013)

Name: Anti-Human CIAO1 IP Recombinant Antibody (SAA0198)
Brand: abinScience
SKU: HF508013
Price: 191 USD
Availability: InStock

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1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HF508013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG2a

Clone ID

SAA0198

Clonality

Monoclonal

Target

WD repeat-containing protein 39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WDR39, CIA1, CIAO1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O76071

RRID

Anti-Human CIAO1 IP Antibody (SAA0198) (abinScience Cat# HF508013, RRID:AB_3729732)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Probable cytosolic iron-sulfur protein assembly protein CIAO1 is a ~37 kDa protein. Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1.

1. Srinivasan, V. et al. (2007) Structure (London, England : 1993) 15, 1246-57. PMID: 17937914

2. Stehling, O. et al. (2013) Cell metabolism 18, 187-98. PMID: 23891004

3. Maio, N. et al. (2024) The Journal of clinical investigation 134. PMID: 38950322

4. Johnstone, RW. et al. (1998) The Journal of biological chemistry 273, 10880-7. PMID: 9556563

5. Ito, S. et al. (2010) Molecular cell 39, 632-40. PMID: 20797633

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CIAO1 IP Antibody (SAA0198)

References

Datasheet

Anti-Human CIAO1 IP Recombinant Antibody (SAA0198).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CIAO1 IP Recombinant Antibody (SAA0198) (HF508013)

Overview

Images

References

Datasheet

SDS

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