

| Catalog No. | HA145014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human COLEC11 Polyclonal Antibody (HA145014) is a rabbit polyclonal antibody detecting COLEC11 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human COLEC11 (Ser151-Met271). | ||||||||
| Target | Collectin-11, Collectin kidney protein 1, CL-K1, COLEC11 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9BWP8 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Collectin-11 (COLEC11) is a ~28 kDa protein. Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. 1. Rooryck, C. et al. (2011) Nature genetics 43, 197-203. PMID: 21258343 2. Henriksen, ML. et al. (2013) Molecular immunology 56, 757-67. PMID: 23954398 3. Venkatraman Girija, U. et al. (2015) BMC biology 13, 27. PMID: 25912189 4. Keshi, H. et al. (2006) Microbiology and immunology 50, 1001-13. PMID: 17179669 5. Hansen, S. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 6096-104. PMID: 20956340 6. Munye, MM. et al. (2017) PLoS genetics 13, e1006679. PMID: 28301481 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-Human COLEC11 polyclonal antibody at 1ug/mL on recombinant Human COLEC11 (Catalog No. HA145012).
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