Anti-Human COMP Recombinant Antibody (SAA1641) (HW810013)

Name: Anti-Human COMP Recombinant Antibody (SAA1641)
Brand: abinScience
SKU: HW810013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW810013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1641

Clonality

Monoclonal

Target

TSP5, Thrombospondin-5, COMP, Cartilage oligomeric matrix protein

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P49747

RRID

Anti-Human COMP Antibody (SAA1641) (abinScience Cat# HW810013, RRID:AB_3727402)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Cartilage oligomeric matrix protein (COMP) is a ~82 kDa protein. Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP).

1. Chen, FH. et al. (2005) The Journal of biological chemistry 280, 32655-61. PMID: 16051604

2. Koelling, S. et al. (2006) Arthritis research & therapy 8, R56. PMID: 16542502

3. Gagarina, V. et al. (2008) The Journal of biological chemistry 283, 648-659. PMID: 17993464

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human COMP Antibody (SAA1641)

References

Datasheet

Anti-Human COMP Recombinant Antibody (SAA1641).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human COMP Recombinant Antibody (SAA1641) (HW810013)

Overview

Images

References

Datasheet

SDS

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