Anti-Human EWSR1 Polyclonal Antibody (HX938014)

Name: Anti-Human EWSR1 Polyclonal Antibody
Brand: abinScience
SKU: HX938014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HX938014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human EWSR1 (Asp353-Arg446).

Target

RNA-binding protein EWS, EWS oncogene, EWS, EWSR1, Ewing sarcoma breakpoint region 1 protein

Purification

Purified by antigen affinity column.

Accession

Q01844

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

RNA-binding protein EWS (EWSR1) is a ~68 kDa protein. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

1. Nguyen, CD. et al. (2011) Journal of molecular biology 407, 273-83. PMID: 21256132

2. Li, KK. et al. (2000) The Journal of biological chemistry 275, 23053-8. PMID: 10767297

Note

For research use only.

Images

References

Datasheet

Anti-Human EWSR1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human EWSR1 Polyclonal Antibody (HX938014)

Overview

Images

References

Datasheet

SDS

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