Human EWSR1 Recombinant Protein (N-GST & C-His) (HX938022)

Name: Human EWSR1 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HX938022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HX938022
Description	Recombinant Human EWSR1 Protein, N-GST & C-His (HX938022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q01844
Protein length	Asp353-Arg446
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EWS, EWS oncogene, EWSR1, Ewing sarcoma breakpoint region 1 protein, RNA-binding protein EWS
Background	RNA-binding protein EWS is a ~68 kDa protein. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. 1. Nguyen, CD. et al. (2011) Journal of molecular biology 407, 273-83. PMID: 21256132 2. Li, KK. et al. (2000) The Journal of biological chemistry 275, 23053-8. PMID: 10767297
Note	For research use only

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Datasheet

Human EWSR1 Recombinant Protein (N-GST & C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human EWSR1 Recombinant Protein (N-GST & C-His) (HX938022)

Overview

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References

Datasheet

SDS

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