Anti-Human F10/Factor X Recombinant Antibody (SAA1800) (HF610013)

Name: Anti-Human F10/Factor X Recombinant Antibody (SAA1800)
Brand: abinScience
SKU: HF610013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HF610013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1800

Clonality

Monoclonal

Target

Stuart factor, Stuart-Prower factor, Coagulation factor X, F10

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P00742

RRID

Anti-Human F10/Factor X Antibody (SAA1800) (abinScience Cat# HF610013, RRID:AB_3727562)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Coagulation factor X (F10) is a ~54 kDa protein. Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. Factor Xa activates pro-inflammatory signaling pathways in a protease-activated receptor (PAR)-dependent manner. Up-regulates expression of protease-activated receptors (PARs) F2R, F2RL1 and F2RL2 in dermal microvascular endothelial cells. Triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL6, in cardiac fibroblasts and umbilical vein endothelial cells in PAR-1/F2R-dependent manner. Triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2, IL6, TNF/TNF, IL-1beta/IL1B, IL8/CXCL8 and IL18, in endothelial cells and atrial tissues.

1. Manithody, C. et al. (2012) Biochemistry 51, 2551-7. PMID: 22409427

2. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037

3. Bukowska, A. et al. (2013) European journal of pharmacology 718, 114-23. PMID: 24041930

4. Shinozawa, E. et al. (2018) Frontiers in pharmacology 9, 1431. PMID: 30568593

5. D'Alessandro, E. et al. (2021) Cells 10. PMID: 34831181

6. Borensztajn, K. et al. (2008) The American journal of pathology 172, 309-20. PMID: 18202198

7. Shrivastava, G. et al. (2022) ImmunoHorizons 6, 373-383. PMID: 35738824

8. Senden, NH. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 161, 4318-24. PMID: 9780208

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human F10/Factor X Antibody (SAA1800)

References

Datasheet

Anti-Human F10/Factor X Recombinant Antibody (SAA1800).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human F10/Factor X Recombinant Antibody (SAA1800) (HF610013)

Overview

Images

References

Datasheet

SDS

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