Anti-Human FCER1A Recombinant Antibody (SAA1531) (HY285013)

Name: Anti-Human FCER1A Recombinant Antibody (SAA1531)
Brand: abinScience
SKU: HY285013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY285013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1531

Clonality

Monoclonal

Target

FcERI, IgE Fc receptor subunit alpha, FCER1A, Fc-epsilon RI-alpha, FCE1A, High affinity immunoglobulin epsilon receptor subunit alpha

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P12319

RRID

Anti-Human FCER1A Antibody (SAA1531) (abinScience Cat# HY285013, RRID:AB_3727292)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A/FcERI) is a ~29 kDa protein. High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity.

Note

For research use only.

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