Anti-Human FCER1A Polyclonal Antibody (HY285014)

Name: Anti-Human FCER1A Polyclonal Antibody
Brand: abinScience
SKU: HY285014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY285014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FCER1A (Lys31-Lys196).

Target

FcERI, IgE Fc receptor subunit alpha, FCER1A, Fc-epsilon RI-alpha, FCE1A, High affinity immunoglobulin epsilon receptor subunit alpha

Purification

Purified by antigen affinity column.

Accession

P12319

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A/FcERI) is a ~29 kDa protein. High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human FCER1A polyclonal antibody at 1ug/mL on recombinant Human FCER1A (Catalog No. HY285012).

References

Datasheet