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Anti-Human FUT8 Recombinant Antibody (SAA1898) (HA263013)

Anti-Human FUT8 Recombinant Antibody (SAA1898)
Anti-Human FUT8 Recombinant Antibody (SAA1898)
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Overview
Catalog No.HA263013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1898
Clonality Monoclonal
Target Glycoprotein 6-alpha-L-fucosyltransferase, Fucosyltransferase 8, Alpha-(1, 6)-fucosyltransferase, Alpha1-6FucT, FUT8, GDP-fucose--glycoprotein fucosyltransferase, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1, 6-fucosyltransferase
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9BYC5
RRID

Anti-Human FUT8 Antibody (SAA1898) (abinScience Cat# HA263013, RRID:AB_3727662)
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Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Alpha-(1,6)-fucosyltransferase (FUT8) is a ~66 kDa protein. Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Fucosylates the reducing GlcNAc residue in complex-type N-glycans attached on the fragment crystallizable (Fc) of IgGs. Fully converts Fc glycoforms containing one or two terminal GlcNAc moieties (G0-GlcNAc and G0).

1. Ihara, H. et al. (2007) Glycobiology 17, 455-66. PMID: 17172260
2. Ng, BG. et al. (2018) American journal of human genetics 102, 188-195. PMID: 29304374
3. Jaroentomeechai, T. et al. (2022) Nature communications 13, 6325. PMID: 36280670
4. Yanagidani, S. et al. (1997) Journal of biochemistry 121, 626-32. PMID: 9133635
Note For research use only.
Images
  • Anti-Human FUT8 Recombinant Antibody (SAA1898)

    SDS-PAGE

    SDS-PAGE for Anti-Human FUT8 Antibody (SAA1898)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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