Anti-Human GARS1/Glycyl-tRNA synthetase Recombinant Antibody (SAA1935) (HW710013)

Name: Anti-Human GARS1/Glycyl-tRNA synthetase Recombinant Antibody (SAA1935)
Brand: abinScience
SKU: HW710013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW710013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1935

Clonality

Monoclonal

Target

Diadenosine tetraphosphate synthetase, Glycine--tRNA ligase, GlyRS, Glycyl-tRNA synthetase, GARS1, Glycyl-tRNA synthetase 1, Ap4A synthetase, GARS

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P41250

RRID

Anti-Human GARS1/Glycyl-tRNA synthetase Antibody (SAA1935) (abinScience Cat# HW710013, RRID:AB_3727699)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Glycine--tRNA ligase (GARS1) is a ~83 kDa protein. Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis.

1. Cader, MZ. et al. (2007) FEBS letters 581, 2959-64. PMID: 17544401

2. Qin, X. et al. (2014) The Journal of biological chemistry 289, 20359-69. PMID: 24898252

3. Oprescu, SN. et al. (2017) Human mutation 38, 1412-1420. PMID: 28675565

4. Guo, RT. et al. (2009) The Journal of biological chemistry 284, 28968-76. PMID: 19710017

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human GARS1/Glycyl-tRNA synthetase Antibody (SAA1935)

References

Datasheet

Anti-Human GARS1/Glycyl-tRNA synthetase Recombinant Antibody (SAA1935).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human GARS1/Glycyl-tRNA synthetase Recombinant Antibody (SAA1935) (HW710013)

Overview

Images

References

Datasheet

SDS

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