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Anti-Human GAS6 Recombinant Antibody (SAA0476), APC (HC347137)

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Overview
Catalog No.HC347137
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesMouse
IsotypeIgG1
Clone IDSAA0476
ConjugationAPC
Clonality Monoclonal
Target AXLLG, Growth arrest-specific protein 6, AXL receptor tyrosine kinase ligand, GAS6, GAS-6
Endotoxin level Please contact with the lab for this information.
Associated products Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Accession Q14393
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Growth arrest-specific protein 6 (GAS6) is a ~74 kDa protein. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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