

| Catalog No. | HW405014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human IFNGR2 (Lys37-Asp240). | ||||||||
| Target | IFN-gamma receptor 2, Interferon gamma receptor beta-chain, Interferon gamma transducer 1, IFN-gamma-R-beta, AF-1, IFN-gamma-R2, IFNGT1, Interferon gamma receptor accessory factor 1, Interferon gamma receptor 2, IFNGR2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P38484 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Interferon gamma receptor 2 (IFNGR2) is a ~37 kDa protein. Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding. 1. Sakatsume, M. et al. (1995) The Journal of biological chemistry 270, 17528-34. PMID: 7615558 2. Kotenko, SV. et al. (1995) The Journal of biological chemistry 270, 20915-21. PMID: 7673114 3. Soh, J. et al. (1994) Cell 76, 793-802. PMID: 8124716 4. Rosenzweig, SD. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3991-9. PMID: 15356148 | ||||||||
| Note | For research use only. |




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