Anti-Human ITGB7 Recombinant Antibody (SAA1982) (HB878013)

Name: Anti-Human ITGB7 Recombinant Antibody (SAA1982)
Brand: abinScience
SKU: HB878013
Price: 196 USD
Availability: InStock

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1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB878013

Description

Anti-Human ITGB7 Recombinant Antibody (SAA1982) (HB878013) is a mouse monoclonal antibody detecting ITGB7 in ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone ID

SAA1982

Target

Gut homing receptor beta subunit, Integrin beta-7, ITGB7

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P26010

RRID

Anti-Human ITGB7 Antibody (SAA1982) (abinScience Cat# HB878013, RRID:AB_3727746)
_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Integrin beta-7 (ITGB7) is a ~86 kDa protein. Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT) (Probable). Integrin ITGA4/ITGB7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Also interacts with VCAM1 and fibronectin, an extracellular matrix component (Probable). It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin (Probable). Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin (Probable).

1. Higgins, JM. et al. (2000) The Journal of biological chemistry 275, 25652-64. PMID: 10837471

2. Chen, J. et al. (2003) Nature structural biology 10, 995-1001. PMID: 14608374

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ITGB7 Antibody (SAA1982)

References

Datasheet

Anti-Human ITGB7 Recombinant Antibody (SAA1982).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human ITGB7 Recombinant Antibody (SAA1982) (HB878013)

Overview

Images

References

Datasheet

SDS