Anti-Human KCNA5 Polyclonal Antibody (HB985014)

Name: Anti-Human KCNA5 Polyclonal Antibody
Brand: abinScience
SKU: HB985014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HB985014

Description

Anti-Human KCNA5 Polyclonal Antibody (HB985014) is a rabbit polyclonal antibody detecting KCNA5. Suitable for Human, Rat, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KCNA5 (Thr106-Gly247).

Target

HPCN1, KCNA5, Potassium voltage-gated channel subfamily A member 5, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv1.5

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P22460

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Potassium voltage-gated channel subfamily A member 5 (KCNA5) is a ~67 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation.

1. Williams, CP. et al. (2002) The Journal of pharmacology and experimental therapeutics 302, 545-50. PMID: 12130714

2. Snyders, DJ. et al. (1993) The Journal of general physiology 101, 513-43. PMID: 8505626

Note

For research use only

Images

References

Datasheet

Anti-Human KCNA5 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human KCNA5 Polyclonal Antibody (HB985014)

Overview

Images

References

Datasheet

SDS

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