Human KCNA5 Recombinant Protein (N-His) (HB985012)

Name: Human KCNA5 Recombinant Protein (N-His)
Brand: abinScience
SKU: HB985012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HB985012
Description	Recombinant Human KCNA5 Protein, N-His (HB985012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P22460
Protein length	Thr106-Gly247
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	HPCN1, KCNA5, Potassium voltage-gated channel subfamily A member 5, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv1.5
Background	Potassium voltage-gated channel subfamily A member 5 is a ~67 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation. 1. Williams, CP. et al. (2002) The Journal of pharmacology and experimental therapeutics 302, 545-50. PMID: 12130714 2. Snyders, DJ. et al. (1993) The Journal of general physiology 101, 513-43. PMID: 8505626
Note	For research use only

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Datasheet

Human KCNA5 Recombinant Protein (N-His).pdf

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Human KCNA5 Recombinant Protein (N-His) (HB985012)

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