

| Catalog No. | HD548014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human KHDRBS3 Polyclonal Antibody (HD548014) is a rabbit polyclonal antibody detecting KHDRBS3. Suitable for Rat, Mouse, and Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human KHDRBS3 (Asn51-Gly176). | ||||||||
| Target | KH domain-containing, RNA-binding, signal transduction-associated protein 3, KHDRBS3, RNA-binding protein T-Star, SALP, SLM-2, SLM2, Sam68-like mammalian protein 2, Sam68-like phosphotyrosine protein | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O75525 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3) is a ~38 kDa protein. RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6. 1. Lee, J. et al. (1999) Gene 240, 133-47. PMID: 10564820 2. Ray, D. et al. (2009) Nature biotechnology 27, 667-70. PMID: 19561594 3. Feracci, M. et al. (2016) Nature communications 7, 10355. PMID: 26758068 4. Cohen, CD. et al. (2005) Journal of the American Society of Nephrology : JASN 16, 1958-65. PMID: 15901763 | ||||||||
| Note | For research use only |
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