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Anti-Human KLB/Beta-klotho Antibody (SAA0157), PE (HV266127)

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Overview
Catalog No.HV266127
Description
Anti-Human KLB/Beta-klotho Antibody (SAA0157), PE [SAA0157] (HV266127) is a human monoclonal antibody detecting Beta-klotho in FCM. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
IsotypeIgG1, kappa
Clone IDSAA0157
ConjugationPE
Clonality Monoclonal
Target Klotho beta-like protein, KLB, Beta-klotho, BetaKlotho, BKL
Endotoxin level Please contact with the lab for this information.
Accession Q86Z14
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Beta-klotho (KLB) is a ~119 kDa protein. Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.

Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
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Formula
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