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Anti-Human KLB/Beta-klotho Monoclonal Antibody (1A138) (HV266025)

Anti-Human KLB/Beta-klotho Monoclonal Antibody (1A138)
Anti-Human KLB/Beta-klotho Monoclonal Antibody (1A138)
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Overview
Catalog No.HV266025
Description
Anti-Human KLB/Beta-klotho Monoclonal Antibody (1A138) [1A138] (HV266025) is a mouse monoclonal antibody detecting Beta-klotho in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG1
Clone ID1A138
Immunogen E. coli - derived recombinant Human KLB / Beta-klotho (Lys2-Pro996).
Target Klotho beta-like protein, KLB, Beta-klotho, BetaKlotho, BKL
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q86Z14
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Beta-klotho (KLB) is a ~119 kDa protein. Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.

Note For research use only.
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  • Anti-Human KLB/Beta-klotho Monoclonal Antibody (1A138)

    SDS-PAGE

    SDS-PAGE for Anti-Human KLB/Beta-klotho Monoclonal Antibody (1A138)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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